I am going to try and get it from Canada. It appears to be the most affordable option for the brand.
I am going to try and get it from Canada. It appears to be the most affordable option for the brand.
for males adequate levels of testosterone is the best dopamine enhancer, and natural....Originally Posted by mopes
I would not be so sure about that... it is a "chicken & egg" thing. And personally, I believe that higher dopamine rather triggers more test production than vice versa
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Seriously? Do you have a reference for that?
My personal neuroscience weblog, you should check it out: The Illuminated Brain - A Weblog on Neuroscience
"It is a capital mistake to theorize before one has data. Insensibly one begins to twist facts to suit theories, instead of theories to suit facts." - Sherlock Holmes
Would love to get the test up a bit higher (540 total t @ 31 years old) but not sure there's much more I can do there. Appreciate the suggestion though.
Clomiphene.
My personal neuroscience weblog, you should check it out: The Illuminated Brain - A Weblog on Neuroscience
"It is a capital mistake to theorize before one has data. Insensibly one begins to twist facts to suit theories, instead of theories to suit facts." - Sherlock Holmes
Yeah I've been reading up on it, waiting to see what my lh/fsh levels come back at...
I've read somewhere that Dr. Shippen uses selegiline to increase testosterone levels in cases of mild hypogonadism and mine were higher than usual while on it.
Males higher on social hierarchies, in other words those with constantly streaming DA in the reward pathway, are known to have much higher testosterone levels
Non-stimulant approach: have a rewarding adolescence.
http://www.ncbi.nlm.nih.gov/pubmed/21741457Adolescent social defeat alters markers of adult dopaminergic function.
Stressful experiences during adolescence can alter the trajectory of neural development and contribute to psychiatric disorders in adulthood. We previously demonstrated that adolescent male rats exposed to repeated social defeat stress show changes in mesocorticolimbic dopamine content both at baseline and in response to amphetamine when tested in adulthood. In the present study we examined whether markers of adult dopamine function are also compromised by adolescent experience of social defeat. Given that the dopamine transporter as well as dopamine D1 receptors act as regulators of psychostimulant action, are stress sensitive and undergo changes during adolescence, quantitative autoradiography was used to measure [(3)H]-GBR12935 binding to the dopamine transporter and [(3)H]-SCH23390 binding to dopamine D1 receptors, respectively. Our results indicate that social defeat during adolescence led to higher dopamine transporter binding in the infralimbic region of the medial prefrontal cortex and higher dopamine D1 receptor binding in the caudate putamen, while other brain regions analyzed were comparable to controls. Thus it appears that social defeat during adolescence causes specific changes to the adult dopamine system, which may contribute to behavioral alterations and increased drug seeking.
In that case, I think I'll go back and change mine.
Your adolescence wasn't rewarding?
My personal neuroscience weblog, you should check it out: The Illuminated Brain - A Weblog on Neuroscience
"It is a capital mistake to theorize before one has data. Insensibly one begins to twist facts to suit theories, instead of theories to suit facts." - Sherlock Holmes
LOL. No kidding. Reading that just depresses me. Stuff that happened so many years ago and was completely out of my control has likely screwed up my neurobiology permanently. Fantastic.
Only in a chemical sense.
There has to be some way to reverse these changes though. I'm sure it's much more difficult than establishing them in adolescence but I think neuroplasticity must offer some hope. Maybe if you experience a few thousand rewarding social interactions in a row, something along those lines.
NeuralFrequency liked this post
Yeah, Sanction, stop posting stuff like that, it just depresses me more..
You think so? I just don't know. I mean that's my hope ultimately, but it seems that even with a marriage, a family of my own and all the rewarding experiences that come with it, my screwed up dysfunctional childhood and adolescence always haunt me. Of course, now I'm just whining, but I really do wonder if stuff like that is permanent, and then that leads to cycle of dysfunction that lasts over generations?
I know that for me personally, my number 1 goal in life is that my children always have a loving, functional home that they feel safe in and can be happy. There is nothing more important for me than that.
mopes liked this post
I quoted one study that had a very limited scope.
Don't underestimate the effects of neuroplasticity/learning, self-insight and a good social environment in adulthood.
Wilco liked this post
I've been interested in selegiline and that would be an added bonus. Have you experienced any tolerance or withdrawal to selegiline in your personal use? Not sure if I should stay away from it given my reaction to Ropinirole
Yes, I experienced all of the above: tolerance to the benefits, gradual development of negative side effects, and negative withdrawal effects. I don't think that is too uncommon either, or everyone would still be taking it. It's one of those things like piracetam, where 100 people try it, and when you poll them 1-2 years later, only a couple continued to use it.
But since you could be part of that 1-2%, I don't know how much value my anecdote is for you (or anyone else).
Last edited by FunkOdyssey; January 26th, 2012 at 04:34 AM.
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