h t t p : / / w w w . brenda-enzymes.org/literature/lit.php4?e=1.1.1.146&r=668636
Coffea arabica fruit extract, corresponding to an italian espresso, inhibits recombinant and endogenous isozyme 11beta-HSD1 in HEK-293 cells up by 80% at 2% of extract, the inhibitory component is heat-stable with considerable polarity, extract blocks 11beta-HSD1-dependent cortisol formation in vivo preventing the subsequent nuclear translocation of the glucocorticoid receptor and abolishes glucocorticoid-induced expression of the key gluconeogenic enzyme phosphoenolpyruvate carboxykinase, at least part of the anti-diabetic effects of coffee consumption is due to inhibition of 11beta-HSD1-dependent glucocorticoid reactivation, overview, the inhibitory effect on isozyme 11beta-HSD1 is 7-10fold higher compared to isozyme 11beta-HSD2
ok so im guessing....
Coffea arabica extracted for caffeine .... AND.... (next post)
Coffea arabica extracted for Polysaccharides
Polysaccharides from hot water extracts of roasted Coffea arabica beans: isolation and characterization
L. Navarini, R. Gilli, V. Gombac, A. Abatangelo, M. Bosco, R. Toffanin
Abstract
A polysaccharide fraction was obtained from the hot water extract of defatted ground dark roasted coffee (pure Coffea arabica blend for espresso brewing technique) by means of classical precipitation methods. This high molecular weight (〈Mw〉=10 900 Da) product was shown to be composed of mannose, galactose, arabinose and traces of proteinaceous material. Further fractionation yielded two different carbohydrate polymers, which were structurally characterized. One polysaccharide was identified as a β-d-(1-4) mannan containing small amounts of galactose and arabinose. The second polysaccharide, obtained in low yield after removal of the mannose-containing polymeric material, was identified as an arabinogalactan. The starting fraction was found to be composed of about 80% (mol basis) of mannan and of about 20% of arabinogalactan. 13C-NMR spectra revealed that the arabinogalactan has a backbone chain of β-(1-3)-d-galactopyranose units. Some of these units were substituted with either terminal β-d-galactose or terminal α-l-arabinofuranose side chains mainly in C-6 position. Both the mannan and the arabinogalactan isolated are structurally related to the polysaccharides originally present in the green coffee beans.
DHEA
I cheated...
"Everything in moderation, including moderation" - Wilde
DHEA?
Like short sleeves, I bare arms
Applied Nutriceuticals FORUM REP
www.appliednutriceuticals.com
Cool contest app nut. Btw welcome to the board!
Mind and Muscle Rep
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5. Hordenine HCl - GaWd
6. Green Tea Extract (Standardized to 95% Polyphenols) - mattj913
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Here's how this contest will work (rules):
* You must be 18 years old or older.
* You must reside in the US or Canada.
* You are allowed ONE ingredient guess per post, with a maximum of 2 posts per day. Multiple ingredients guessed in a post or, more than 2 guesses per day, will disqualify you from winning on that day!
* Your guess must be the exact ingredient. AppNut will have the say on whether your guess is correct.
* The first post, that identifies an ingredient, is the winner.
* You can win only ONE bottle in this contest or any other contest we may run.
* Product will ship, to the Winners, once the product is released.
Applied Nutriceuticals FORUM REP
MANAGER
evodiamine extract
DHEA ......
3,3 Diiodo L-Thyronine?
That is my official WELCOME TO M&M guess![]()
DHEA is a winner! By "cheated" I assume you mean you were resourceful in your research. Since you were the first person to guess DHEA, you get to claim the prize. Please PM me your shipping info.
To others who ventured DHEA, good guess but a little too late. Still five ingredients left, which means five more prizes to claim.
Like short sleeves, I bare arms
Applied Nutriceuticals FORUM REP
www.appliednutriceuticals.com
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