Modafinil
Posted 23 October 2009 - 02:13 PM (#1)
I'm diagnosed with ADD/Depression. After doing the whole med-go-round (SSRIs, Ritalin, Bupropion), I'm currently on deprenyl and although it's better than nothing I still need something more.
I'm a "third world monkey" (Par Deus), so no Adderall around here for me to take MOAR. Just plain old school Ritalin, Concerta (expensive as FUCK!), and Modafinil, which has just arrived around here.
What do you guys think about Modafinil? Does anyone knows exactly how it works?
As always, thanks!
Posted 25 October 2009 - 12:54 AM (#2)
Posted 25 October 2009 - 02:11 AM (#3)
Which means that it will keep you awake but not necessarily attentive or happy.
Posted 25 October 2009 - 11:13 AM (#4)
Posted 25 October 2009 - 12:09 PM (#5)
No dexadrine spansules in your banana republic?

However beautiful the strategy, you should occasionally look at the results... - Winston Churchill
Posted 25 October 2009 - 01:58 PM (#6)
Posted 25 October 2009 - 04:19 PM (#7)
very low dose deprenyl equals how much in your experience?
I was taking 7.5mg, then down to 5mg. I'm on 2.5mg now, but I've started this dosage just today.
Posted 25 October 2009 - 04:23 PM (#8)
Unfortunately, no.
just Ritalin, Concerta and now Modafinil.
Posted 25 October 2009 - 05:09 PM (#9)
My experience is very similar. I liked taking about 2.5 mg deprenyl a week. Even that though wore off after about a month. Im starting to think a lot of ADD is just caused by bad sleep habits and poor coping skills along with anxiety.
Posted 25 October 2009 - 06:23 PM (#10)
just Ritalin, Concerta and now Modafinil.
Where the heck do you live? The moon?

However beautiful the strategy, you should occasionally look at the results... - Winston Churchill
Posted 26 October 2009 - 03:56 AM (#11)
For the record, amphetamine is pretty much only widely prescribed in the U.S.
EU and most of Asia are shit out of luck (although UK might be somewhat better).
I live in an EU country and managed to get dexamphetamine only after a very lenghty licence ordeal (99 % of patients get Concerta/Ritalin or Strattera).
Oh and no Spansules here either only IR.
Posted 26 October 2009 - 11:37 PM (#12)
I was taking 7.5mg, then down to 5mg. I'm on 2.5mg now, but I've started this dosage just today.
I seem to do better on 1.25mg - 2.5mg once in the morning. It's deceiving because there is really no acute effect anymore after you have been taking it daily for a long time. I found out it was working when I took a few days off and suddenly couldn't focus on shit anymore.
I've said it before on here. The deprenyl definitely helps, but everything else in my life has to be in order. In order of importance those things would be sleep, diet, and enough exercise.
Posted 27 October 2009 - 12:43 AM (#13)
I've said it before on here. The deprenyl definitely helps, but everything else in my life has to be in order. In order of importance those things would be sleep, diet, and enough exercise.
I assume you are taking it after a meal?
Posted 27 October 2009 - 07:47 PM (#14)
I do take it after a small meal, protein shake and some oatmeal in the morning. I don't actually swallow it though. I keep it under my tongue until it's completely dissolved. I don't have the sublingual tabs but they still break down very easily.
Posted 13 July 2010 - 10:28 AM (#15)
LOL.
I'm from Brazil.
Bumping an old thread to report...
I'm having some success with Methylphenidate and Modafinil. I'm taking 7,5mg of Ritalin (4x/day, spaced in 4-hour intervals) and 100mg of Modafinil (in the morning with my first methylphenidate dose).
5mg of methylphenidate isn't enough for focus. if I try 10mg, I feel sleeeeeeeeeeepy.
I'm thinking about dropping Modafinil even lower (50mg) because of some spacey feeling I'm getting randomly. They were more severe at 200mg. At 300mg I was bordering psychosis. That's why I think it's the Modafinil.
I miss the sexual urge I got on higher dosages of Modafinil. On the other hand, it isn't nice if all you want is bang women all the time and can't do other things.
Does anyone here have any experiences on lower doses of Modafinil?
Posted 13 July 2010 - 03:41 PM (#16)
Posted 13 July 2010 - 07:50 PM (#17)
Theoretically, there is potential for interaction, but the affinity of modafinil for DAT is relatively low compared to amphetamine. I've combined the two before without problems (YMMV). I agree with your note of caution though.
As to the OP, Modafinil was really, really close to being approved for treatment of ADD/ADHD in the U.S., but was ditched by the FDA over concerns around development of Steven Johnson's syndrome in children. Not much of a concern for adults though, since kids need about as much as adults to reach effectiveness, but with much higher mg/kg dosing range (ages 6-17 dose at around 170-425mg).
But remember kids, just 'cause a drug is a stimulant and effectively treats ADD/ADHD, doesn't mean it will feel (at all) like amphetamine.
"When men are most sure and arrogant they are commonly most mistaken, giving views to passion without that proper deliberation which alone can secure them from the grossest absurdities." - David Hume
Posted 13 July 2010 - 08:40 PM (#18)
As to the OP, Modafinil was really, really close to being approved for treatment of ADD/ADHD in the U.S., but was ditched by the FDA over concerns around development of Steven Johnson's syndrome in children. Not much of a concern for adults though, since kids need about as much as adults to reach effectiveness, but with much higher mg/kg dosing range (ages 6-17 dose at around 170-425mg).
But remember kids, just 'cause a drug is a stimulant and effectively treats ADD/ADHD, doesn't mean it will feel (at all) like amphetamine.
hey Dopamine...
what dose do you use to treat ADD?
Modafinil alone:
For me, 300mg was too much. stomach pains, diarrhea, and feeling/acting a little bit weird to say the least.
200mg... well... my focus wasn't improved. And I had some sides too, felt spacey.
On both dosages I was yawning all day long. It started around T+3 and lasted the entire day.
can't comment on 100mg, because I started that dosage when I decided to add the Ritalin to the combo.
Posted 14 July 2010 - 12:16 AM (#19)
what dose do you use to treat ADD?
Modafinil alone:
For me, 300mg was too much. stomach pains, diarrhea, and feeling/acting a little bit weird to say the least.
200mg... well... my focus wasn't improved. And I had some sides too, felt spacey.
On both dosages I was yawning all day long. It started around T+3 and lasted the entire day.
can't comment on 100mg, because I started that dosage when I decided to add the Ritalin to the combo.
For adult ADD/ADHD - one 200mg dose upon rising, allowing 20-30 minutes before ingesting any food, consistently for at least 3 weeks. If side effects arise, split the dose into two 100mg doses, one at rising and the other in the early to middle afternoon.
Remember that rapidly fluctuating your dosage will dramatically decrease the likelihood of successful treatment.
"When men are most sure and arrogant they are commonly most mistaken, giving views to passion without that proper deliberation which alone can secure them from the grossest absurdities." - David Hume
Posted 14 July 2010 - 08:29 AM (#20)
Posted 14 July 2010 - 09:38 AM (#21)
Posted 15 July 2010 - 07:21 PM (#22)
"When men are most sure and arrogant they are commonly most mistaken, giving views to passion without that proper deliberation which alone can secure them from the grossest absurdities." - David Hume
Posted 15 July 2010 - 07:44 PM (#23)
BTW, that is the President of ILADS and the author of this presentation I just posted on the forum a couple days ago:
Infectious causes of psychiatric disorders and treatment
He likes modafinil during the day and pregabalin at night to normalize amplitude of circadian rhythm in patients with disturbed sleep and poor daytime functioning.

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