norethindrone SHBG blocker
Posted 09 December 2007 - 05:20 PM (#1)
It is reputed to be a powerful blocker of SHBG. Can I use it with ATD and caprylic acid to for an anti- E ,anti- shbg .
I have always responded well to progestin like steroids , like tren.
Would I need to run some winstrol in this stack , and some anti progestagenic gyno substance?
Probably gonna trash the stuff , unless some one from experience has used it and it worked great.
I know most people stack it with tren or winny , or so I've read.
Posted 09 December 2007 - 07:33 PM (#2)
In my n=1 experience, gyno from strong progestins only occurs in the presence of estrogen. I ran tren acetate solo years back at a rather high dose and had no trouble. Tren acetate and test prop had me growing boobies from week one.
Posted 09 December 2007 - 08:07 PM (#3)
Heavy_Lifter85, on Dec 9 2007, 07:33 PM, said:
Its a synthetic progesterone most commonly used in oral contraceptives.

However beautiful the strategy, you should occasionally look at the results... - Winston Churchill
Posted 09 December 2007 - 08:22 PM (#4)
Benson, on Dec 9 2007, 06:07 PM, said:
Male contraception too, it turns out!
-----------------------------------------------------------
Norethisterone enanthate plus testosterone undecanoate for male contraception: effects of various injection intervals on spermatogenesis, reproductive hormones, testis, and prostate.
Meriggiola MC, Costantino A, Saad F, D'Emidio L, Morselli Labate AM, Bertaccini A, Bremner WJ, Rudolph I, Ernst M, Kirsch B, Martorana G, Pelusi G.
Department of Obstetrics and Gynecology, S. Orsola Hospital, Via Massarenti 13, 40138 Bologna, Italy. crismeri@med.unibo.it
The goal of this study was to find the most favorable injection interval of norethisterone enanthate (NETE) plus testosterone undecanoate (TU) in terms of gonadotropin, sperm suppression, and prostatic effects. Fifty normal men were randomly assigned to receive NETE 200 mg plus TU 1000 mg every 8 wk (n = 10), every 12 wk (n = 10), every 6 wk for 12 wk and then every 12 wk (n = 10), and every 6 wk for 12 wk and thereafter TU 1000 mg plus placebo every 12 wk (n = 10), and placebo plus placebo every 6 wk for 12 wk and then every 12 wk (n = 10) for 48 wk. Semen analyses, blood drawings, physical examinations, and prostate ultrasounds were performed throughout the study. Of the men in the 8-wk injection group, 90% (nine of 10) achieved azoospermia, compared with 37.5% (three of eight) in the 12-wk injection group (P = 0.019). TU plus placebo injected every 12 wk did not maintain sperm suppression. Prostate volumes did not change significantly in either group. In conclusion, these data suggest that the combined administration of NETE and TU at 8-wk intervals represents an effective hormonal contraceptive regimen.
PMID: 15634716 [PubMed - indexed for MEDLINE]
Posted 14 December 2007 - 01:26 AM (#5)
Posted 14 December 2007 - 04:11 PM (#6)
thebrakes, on Dec 14 2007, 02:26 AM, said:
I have a horribly high amount of DHT , im 22 and I have a hairy back , acne on , my back, oily skin and I have been having mpb since I was 17.
Could a nandrolone like norethindrone really combat this? can I run it without test? im not gonna stack it with winny or with tren? So stand alone aside from anti E and normal supps?
Im not able to have sex right now so nandro dick is not a problem. I just want to gain as much weight as I can .
Posted 14 December 2007 - 06:08 PM (#7)
deandestructo, on Dec 14 2007, 04:11 PM, said:
Could a nandrolone like norethindrone really combat this? can I run it without test? im not gonna stack it with winny or with tren? So stand alone aside from anti E and normal supps?
Nandrolone will bind to the AR and displace more androgenic compounds like DHT and T.
If you want to reduce DHT, a 5AR inhibitor would seem to be a better choice.

However beautiful the strategy, you should occasionally look at the results... - Winston Churchill
Posted 15 December 2007 - 12:07 AM (#8)
should i trash it or save it for tren?
Posted 15 December 2007 - 06:13 AM (#9)
deandestructo, on Dec 15 2007, 12:07 AM, said:
If your stuff was nandrolone, aka deca-durabolin, then I'd say you might want to be all over it because in addition to its anti-androgenic effects, its powerfully anabolic. Your norethindrone, OTOH, has no anabolic effect that I know of and it seems to me like an invitation to gyno and other problems with nothing gained for your efforts.

However beautiful the strategy, you should occasionally look at the results... - Winston Churchill
Posted 15 December 2007 - 08:57 AM (#10)
Posted 17 December 2007 - 08:29 AM (#11)
Benson, on Dec 15 2007, 03:13 AM, said:
firstly, it's DHN that binds strongly to ARs in the scalp, skin and prostate, and as a very mildly androgenic steroid it promotes less androgenicity (when taken without test, of course)
i believe norethindrone does have a noteworthy anabolic effect. it's in vida IIRC. dont have time to search right now...but still, for muscle mass, this is not the right steroid. not at all.
Posted 17 December 2007 - 12:34 PM (#13)
thebrakes, on Dec 17 2007, 08:29 AM, said:
I'd be surprised if it was substantial. This is a common progestin component in oral contraceptives.
If I am wrong, it would be nice because its not controlled and its orally active.

However beautiful the strategy, you should occasionally look at the results... - Winston Churchill
Posted 17 December 2007 - 01:16 PM (#14)
but like i've stated earlier ...I know people stack it wit winny and tren ........
Posted 18 December 2007 - 09:38 AM (#15)
Molecular Weight(base):274.4022
Molecular Weight (ester): 150.174
Formula (base): C18 H26 O2
Formula (ester): C9 H10 O2
Melting Point (base): 122-124°C
Melting Point (ester): 20°C
Manufacturer: Organon
Effective Dose (Men): 200-600mgs/week (2mg/lb of Bodyweight)
Effective Dose (Women): 50-100mgs/week
Active life: 5 days
Detection Time: Up to 12 months
Androgenic/Aabolic ratio: 37:125
From: Steroid.com
Posted 18 December 2007 - 06:48 PM (#16)
Norethindrone has a MW of 298.4
I think you guys might be confusing this stuff with norethandrolone (Nilevar) a legit, if somewhat side-effect plagued, anabolic steroid.

However beautiful the strategy, you should occasionally look at the results... - Winston Churchill
Posted 18 December 2007 - 10:11 PM (#17)

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