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  1. #1
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    What effect would it have on dopamine and prolactin if there was sustained sexual stimulation but it was stopped before reaching orgasm? Assuming one had the willpower to do this, would it boost dopamine? Maybe enhance motivation and drive?

    I may be mistaken but I remember reading that some of the kamasutra is based on this.

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    I don't know about kamasutra, but some of the Taoist literature advocates people not orgasming(or is it ejaculating?). It may raise DA temporarily. In my experience stimulation stopping before orgasm may not be a good thing-I prefer not doing anything to disturb my body's normal state since I don't know the specfics of what would happen & there may be a rise in T which may not be good. Maybe you can try PubMed. There's this study on abstinence raising T after 7 days but it being lowered after orgasm. Also orgasm causes prolactin which inhibits DA to rise.

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    One has to be more specific when talking about changes in central transmitter levels. Meaning, synaptic DA concentrations vary widely depending on what dopaminergic pathway one is focused on and what behavior or drug-challenge is present. In the case of sex, I believe the mesolimbic DA reward pathway is activated (i.e. increased transmission/signaling to the striatum from DA neurons projecting from the VTA) but am not sure if the mesocortical pathway is activated, it might even be inhibited. Nigrostriatal DA is mostly motor-related, so I would presume no major change there but am not sure. There are of course other smaller and less canonical DA pathways in the CNS. Point being, the phrase "increased DA" is too non-specific in the absence of some neuroanatomical context.
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    Senior Member methodice's Avatar
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    Yes I would say it would increase DA. And I would say it would boost motivation and drive for sexual things. Will it transfer into making you do your study that you should be doing? Or enthuse you into finishing a report for work or doing the mowing of your lawn? Probably not.
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    <div class='quotetop'>QUOTE (Chaos Theory @ Jul 21 2009, 12:02 PM) <{POST_SNAPBACK}></div><div class='quotemain'>What effect would it have on dopamine and prolactin if there was sustained sexual stimulation but it was stopped before reaching orgasm? Assuming one had the willpower to do this, would it boost dopamine? Maybe enhance motivation and drive?

    I may be mistaken but I remember reading that some of the kamasutra is based on this.</div>

    I have long experimented with this. Simplistically, in the sense you describe, i would say yes. But distinction must be made between ejaculation and orgasm (ejaculation is what you want to be concerned with). and as rightly said above, the pathways involved are complex, you need to consider also other neurotransmitters and hormones such as serotonin, oxytocin, norepinephrine etc. You can't consider D in isolation.

    based on my n=1 experience, with no medical data to back me up:
    * complete abstinence (from orgasm, ejaculation and sexual stimulation) acutely increases my 'motivation and drive' and I'm guessing increases Dopamine.

    * abstinence from ejaculation but with frequent and significant stimulation can have two effects:
    a) If i'm with a partner, the result is positive drive, well-being etc but without the calm of ejaculation. I'd say it's a positive, beneficial increase in D, perhaps of magnitude greater than with complete abstinence.

    B) If i'm solo i'm left feeling wired, irritable, 'driven' but without direction and unproductive. It is absolutely not a productive use of time if you're thinking of using masturbation without ejaculation to increase D. I'd say it's counter productive - increased catecholamines, NE and E etc without elevating serotinin, oxytocin. You're left feeling stressed. So I'd say un-beneficial increase in D.

    Arousal means elevated dopamine. Not ejaculating sustains the period of arousal - whereas orgasm releases prolactin, almost 400% above baseline in one study i remember, and prolactin and dopamine generally work against each other. This is what is responsible for the refractory period. so if you skip ejaculation, you skip the prolactin increase, and dopamine should continue to be elevated.

    you should be concerned with ejaculation rather than orgasm, i think that's what's involved in terms of neurotransmitters and what not. some taoists and tantric sex types claim they can orgasm without ejaculation and that that's not supposed to increase prolactin/decrease dopamine.

    hope that helps

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    FWIW, orgasm/ejaculation with a partner makes your prolactin higher(400% above baseline) than just doing so w/o. Some of the hormones involved with orgasm/ejaculation are prolactin, oxytocin(bonding, anxiety, certain learning & memory functions are impaired by centrally administered oxytocin) and vasopressin(memory).

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