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  1. #1
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    N-Methyl-Beta-Methylphenylethylamine HCL

    This is a truly unique and novel compound, and one of compounds that sets Phenadrine apart from competition. Chances are you are familiar with the pharmacological pathways of Beta-Phenylethylamine (PEA). You may also be familiar with N-Methyl-Beta-Phenylethylamine HCL. Yet, do not confuse N-Methyl-Beta-Phenylethylamine HCL with our much more potent agent, N-Methyl-Beta-Methylphenylethylamine HCL with several methyl groups that render it super stable and remorselessly effective. This novel agent works! That simple!

    But why are PEA and its molecular derivatives even important for fat loss?



    A remarkable compound, even in its pure form, Beta-Phenylethylamine (PEA), a catecholamine precursor and nutrient found in chocolate, is known to be a very clean stimulant with the remarkable ability to achieve central-nervous-system stimulation without producing nervousness or the jittery feeling associated with other stimulants. Like norepinephrine, the body?s most potent endogenous fat-burning hormone, PEA acts on alpha-receptors in the brain, triggering the release of the ?feel-good? hormone, dopamine (3,4-dihydroxy-phenethylamine) in neural cells. PEA is also responsible for chocolate?s effect on mood, sense of satiety, reduced food cravings, mild euphoria, as well as increased metabolic rate (by modulating thyroid function). Also known as a neuromodulator, PEA promotes mental alertness, focus and concentration. By regulating catecholamines such as epinephrine (adrenaline) and norepinephrine (noradrenaline) that act on hormone-sensitive lipase, the rate-limiting enzyme in the mobilization of fatty tissue from storage cites, PEA elevates the metabolic rate, ultimately leading to increased fat burning. Unfortunately, PEA is rapidly metabolised in the body by type B monoamine oxidase and has a limited ability to cross the blood-brain barrier, thus preventing it from unleashing its full effects. The challenge was to obtain a form of PEA with a type B monoamine-oxidase inhibitor property. N-Methyl-Beta-Phenylethylamine HCL is an N-Methyl derivative of Beta-Phenylethylamine. This methylated form of PEA is dramatically more potent than pure PEA, and takes PEA?s CNS stimulation and fat-burning several notches higher. While we could have used this compound, we decided to aim still higher. Now enters N-Methyl-Beta-Methylphenylethylamine HCL. This novel and carefully engineered unique agent represents the most potent form of PEA ever developed. It is not an N-Methyl derivative of N-Methyl-Beta-Phenylethylamine HCL, rather an N-Methyl derivative of methylated Beta-Phenylethylamine HCL! It is like ?double methylation?! Such compounds do not come more potent than this! Technically speaking, we astronomically boosted the pharmacokinetic value of PEA! This ?double methylated? form unites the finest properties of PEA such as easily crossing the blood-brain barrier to elevate feelings of euphoria, intensifying fat-burning due to optimised beta-receptor agonism while demonstrating unprecedented stability to B monoamine oxidation, implying a longer-lasting and significantly more intensive overall action. Our N-Methyl-Beta-Methylphenylethylamine HCL is by far the most potent designer fat-loss agent ever developed, and you would not find it in many of fat-loss products around. It elevates the potency of our synergistic blend to never-before-seen levels! You will be convinced!

  2. #2
    Senior Member The Bionic Man's Avatar
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    While that's a nice write-up (yes, I know it's from the manufacturer), the fact that if you Google N-Methyl-Beta-Methylphenylethylamine HCL, this is the only hit you get, leads me to believe this is nothing "new" or "novel", simply the company making up a name for PEA or one of it's analogues. Not saying anything negative, it looks like a solid product...



    They tout this particular ingredient as being "double-methylated". To me, that doesn't sound like a good thing, but my interpretation of methylated refers to pro-hormones and pro-steroids. They sure do put a good spin on this ingredient in the write-up.



    Strangely enough, in their notes, there's not one mention of N-Methyl-Beta-Methylphenylethylamine HCL.

  3. #3
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    Yeah I read about this on AM, but I'm not interested in the product as a whole, just curious about this specific ingredient.



    I think I'll stick to Caffeine and PEA for now.

  4. #4
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    Definitely not a new compound. Shulgin actually speculated that it would be of little use since the beta carbon does little to increase its bioavailability. Adding a methyl to the alpha carbon, however (as in amphetamine), decreases its molecular amphipathism (increased BBB transduction), and decreases its ability to be oxidized.

  5. #5
    Senior Member nelix's Avatar
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    <div class='quotetop'>QUOTE (The Bionic Man @ Aug 28 2008, 01:26 AM) <{POST_SNAPBACK}></div><div class='quotemain'>While that's a nice write-up (yes, I know it's from the manufacturer), the fact that if you Google N-Methyl-Beta-Methylphenylethylamine HCL, this is the only hit you get, leads me to believe this is nothing "new" or "novel", simply the company making up a name for PEA or one of it's analogues. Not saying anything negative, it looks like a solid product...

    They tout this particular ingredient as being "double-methylated". To me, that doesn't sound like a good thing, but my interpretation of methylated refers to pro-hormones and pro-steroids. They sure do put a good spin on this ingredient in the write-up.

    Strangely enough, in their notes, there's not one mention of N-Methyl-Beta-Methylphenylethylamine HCL.</div>

    In my experience 2 methyl = awesome (mdma yay)
    But I imagine this is not exactly a rule.

    <div class='quotetop'>QUOTE (IronFist @ Aug 28 2008, 04:15 AM) <{POST_SNAPBACK}></div><div class='quotemain'>Definitely not a new compound. Shulgin actually speculated that it would be of little use since the beta carbon does little to increase its bioavailability. Adding a methyl to the alpha carbon, however (as in amphetamine), decreases its molecular amphipathism (increased BBB transduction), and decreases its ability to be oxidized.</div>
    I have Pihkal, I'd love a citation.


  6. #6
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    <div class='quotetop'>QUOTE (IronFist @ Aug 27 2008, 10:15 AM) <{POST_SNAPBACK}></div><div class='quotemain'>Definitely not a new compound. Shulgin actually speculated that it would be of little use since the beta carbon does little to increase its bioavailability. Adding a methyl to the alpha carbon, however (as in amphetamine), decreases its molecular amphipathism (increased BBB transduction), and decreases its ability to be oxidized.</div>


    Good post....I like to see this kind of shit,right out of the blue and all.

    Welcome to the board.



  7. #7
    Senior Member Frangible's Avatar
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    <div class='quotetop'>QUOTE (Colin @ Aug 28 2008, 12:02 AM) <{POST_SNAPBACK}></div><div class='quotemain'>Good post....I like to see this kind of shit,right out of the blue and all.

    Welcome to the board.</div>

    Indeed, I think I'm in love. [img]style_emoticons/<#EMO_DIR#>/wub.gif[/img]
    <span style="color:#660000"><span style="font-size:8pt;line-height:100%"><span style="font-family:Arial Narrow">"... </span></span></span><span style="font-family:Arial Narrow"><span style="font-size:8pt;line-height:100%"><span style="color:#8b0000">fresh bread, which deforms elastically is not frangible." --Wikipedia</span></span></span>

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    <div class='quotetop'>QUOTE (nelix @ Aug 27 2008, 09:37 PM) <{POST_SNAPBACK}></div><div class='quotemain'>In my experience 2 methyl = awesome (mdma yay)
    But I imagine this is not exactly a rule.</div>

    MDMA has a similar structure to methamphetamine (an alpha methyl, and a methyl coming directly off the Nitrogen) except with a cyclic di-methoxy derivative coming off the benzene ring which ascribes it its psychotropic properties.

  9. #9
    Senior Member The Bionic Man's Avatar
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    I also just found this one:

    4-Hydroxy-Phenethylamine

    which, after very little research, is a much cooler way of saying Tyramine

  10. #10
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    <div class='quotetop'>QUOTE (The Bionic Man @ Aug 28 2008, 06:14 PM) <{POST_SNAPBACK}></div><div class='quotemain'>I also just found this one:

    4-Hydroxy-Phenethylamine

    which, after very little research, is a much cooler way of saying Tyramine</div>

    haha

  11. #11
    Senior Member nelix's Avatar
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    <div class='quotetop'>QUOTE (IronFist @ Aug 29 2008, 04:02 AM) <{POST_SNAPBACK}></div><div class='quotemain'>MDMA has a similar structure to methamphetamine (an alpha methyl, and a methyl coming directly off the Nitrogen) except with a cyclic di-methoxy derivative coming off the benzene ring which ascribes it its psychotropic properties.</div>
    I always liked alpha methyl tryptamine, but while having a steeper dose response curve, 5 methoxy alpha methyl tryptamine to be less interesting, I dunno what contrast I'm trying to grasp here, but I wish I knew more.

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