Nerve Regeneration Supplements

**Pirate** · April 22nd, 2007, 02:04 AM

What supplements or drugs help with nerve regeneration? I've got serious nerve damage from a herniated disk, and I'm just staring physical therapy. I appreciate any leads.

**ScottL** · April 22nd, 2007, 02:40 AM

Use the search engine as there is a long thread on this.

**kwun** · April 23rd, 2007, 02:17 AM

Originally Posted by ScottL' post='398473' date='Apr 21 2007, 09:40 PM

Use the search engine as there is a long thread on this.

could you please post a link...thanks

**ScottL** · April 23rd, 2007, 09:27 AM

http://www.mindandmuscle.net/forum/index.p...34&hl=nerve

**Pirate** · April 23rd, 2007, 11:40 AM

thanks!

**andr3as** · April 23rd, 2007, 12:06 PM

Clenbuterol stimulates IGF-1

**kwun** · April 24th, 2007, 02:38 AM

Originally Posted by ScottL' post='398638' date='Apr 23 2007, 04:27 AM

http://www.mindandmuscle.net/forum/index.p...34&hl=nerve

thanks

babyblu · April 25th, 2007, 01:59 AM

Originally Posted by uniquenutrition' post='398979' date='Apr 24 2007, 08:43 PM

Idebenone, R-dihydrolipoic acid.

I think I caused some nerve damage from an igf injection into my calf (from the AA). I have had numbness on the outside of my leg, a 'surface-deep' type of numbness, that extends from the outer head down to the ankle. I had just decided it would be a minor irritation I would hav to live with.

What do you think about SOD or mitoquinone for nerve regeneration?

thanks,

bb

**Dopamine** · April 25th, 2007, 06:15 AM

Aswagandha, ALCAR (possibly the arginate form), Huperzine A. Studies on Hydergine wrt NGF are virtually non-existent. Alpha Lipoic acid as a coenzyme appears to increase (in one study) NGF in mouse astroglial cells, inducing a similar effect as other coenzymes: PQQ, pyrroloquinoline quinone; and TOPA, 3-(2,4,5-trihydroxyphenyl)-DL-alanine.

The medium-chain fatty acid octanoic acid is reported to increase NGF in PC12 cells (from rat pheochromocytoma).

Prostaglandins are reported to increase NGF and BDNF levels "in rat astrocyte cultures."

Dopamine agonists (e.g. pergolide, cabergoline) are reported to increase GDNF and NGF synthesis in "cultured rat astrocytes."

Neurochem Res. 1995 Jan;20(1):1-9. "Neurite outgrowth in PC12 cells stimulated by acetyl-L-carnitine arginine amide." Taglialatela G, Navarra D, Olivi A, Ramacci MT,Werrbach-Perez K, Perez-Polo JR, Angelucci L. PMID: 7739750.

Biochem Pharmacol. 1992 Aug 4;44(3):577-85. "Stimulation of nerve growth factor receptors in PC12 by acetyl-L-carnitine." Taglialatela G, Angelucci L, Ramacci MT, et al. PMID: 1324679.

Acta Pharmacol Sin. 2005 Jun;26(6):673-8. "Effects of huperzine A on secretion of nerve growth factor in cultured rat cortical astrocytes and neurite outgrowth in rat PC12 cells." Tang LL, Wang R, Tang XC. PMID: 15916732

Br J Pharmacol. 2005 Apr;144(7):961-71. "Neuritic regeneration and synaptic reconstruction induced by withanolide A." Kuboyama T, Tohda C, Komatsu K. PMID: 15711595.

Biochem Mol Biol Int. 1993 Jul;30(4):615-21. "Stimulation of nerve growth factor synthesis/secretion in mouse astroglial cells by coenzymes." Murase K. PMID: 8401318.

Neuroscience. 2007 Apr 13; [Epub ahead of print]. "Induction of neurite outgrowth in PC12 cells by the medium-chain fatty acid octanoic acid." Kamata Y, et al. PMID: 17434686.

Life Sci. 2003 Jun 20;73(5):617-26. "Effects of dopamine agonists bromocriptine, pergolide, cabergoline, and SKF-38393 on GDNF, NGF, and BDNF synthesis in cultured mouse astrocytes." Ohta K, et al. PMID: 12770616 [PubMed - indexed for MEDLINE]

FEBS Lett. 2004 Mar 26;562(1-3):211-5. "Prostaglandins are powerful inducers of NGF and BDNF production in mouse astrocyte cultures." Toyomoto M, et al. PMID: 15044028 [PubMed - indexed for MEDLINE]