Fat Loss Aids: Raspberry Ketones

Posted on Mar 31, 2011 in Fat Loss Aids, Supplements

Raspberry Ketones are known less commonly as Rheosmin and Rasketone. Raspberry Ketones are found in red raspberries, and are the constituent primarily responsible for the odor of raspberries. Raspberry Ketones are either extracted from red raspberries or made synthetically, and are used as a food additive for their fruity odor.

Raspberry Ketones may have use as a fat loss aid. In mice, Raspberry Ketones have been shown to increase the breakdown of fat by norepinephrine, as well as stimulate the release of norepinephrine to some degree. Raspberry Ketones were found to cause the enzyme hormone-sensitive lipase (HSL) to translocate into fat cells. HSL is responsible for the break down of fat into fatty acids to be burned as energy, which can be accomplished once it is within the fat cell. Raspberry Ketones were also shown to stimulate the release of norepinephrine, providing a mild stimulant effect and further aiding in fat breakdown.

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At this point there is no human research available on the use of Raspberry Ketones for fat loss, but anecdotal evidence does seem to support the effects observed in mice. Users of Raspberry Ketones steady, long lasting boost in energy levels likely due to increased body fat release. Users also report a warming feeling indicating increased calorie burn.

The typical effective dosage range for Raspberry Ketones is 200-1000 mg daily in 2-3 divided doses. Taking large amounts at once (< 500 mg) is known to cause stomach irritation in some users. Raspberry Ketones are included in many fat loss supplements, and can also be purchased alone in capsules or as a powder.

References

1. Morimoto C, Satoh Y, Hara M, Inoue S, Tsujita T, & Okuda H. (2005). Anti-obese action of raspberry ketone. Life Sciences. 77(2), 194-204.

2. Park KS. (2010). Raspberry ketone increases both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes. Planta Medica. 76(15), 1654-8.

3. Choi HS. (2006). Lipolytic effects of citrus peel oils and their components. Journal of Agricultural and Food Chemistry. 54(9), 3254-8.

4. Beekwilder J, van der Meer IM, Sibbesen O, Broekgaarden M, Qvist I, Mikkelsen JD, & Hall RD. (2007). Microbial production of natural raspberry ketone. Biotechnology Journal. 2(10), 1270-9.

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